The UN says hospitals, clinics and ambulances have also come under attack.
In the more densely-populated western parts of the Eastern Ghouta, analysis carried out by the UN in December had already identified approximately 3,853 destroyed buildings, 5,141 severely damaged buildings and 3,547 moderately damaged buildings.
Jobar
Jobar has suffered the worst damage in areas so far assessed. Some 93% of the buildings had been damaged or destroyed by December.
It was an active frontline for many months and the civilian population has fled. Only armed groups remain.
Neighbouring Ein Tarma, which became home to many of those who fled Jobar, was the focus of a government offensive in June 2017.
A sharp increase in shelling and air strikes forced Ein Tarma's residents and displaced families to flee to other areas of the Eastern Ghouta.
A total of 71% of the area's buildings had been damaged or destroyed by December. More than 75% of the pre-conflict civilian population has fled.
Zamalka
Zamalka has the third highest rate of damage in the Eastern Ghouta area assessed by the UN. Some 59% of buildings had been damaged or destroyed by December.
There has been no water or electricity supply for at least two years, and more than 75% of the pre-conflict civilian population has fled.
The intensified bombardment in February saw the area suffer further loss of life and damage levels are certain to have risen beyond those of December.
Hamouria
Due to Hamouria's more central location within the Eastern Ghouta, the amount of damage assessed in December was lower than other areas. Some 11% of buildings had been damaged or destroyed.
However, the area has come under repeated attack during the latest round of bombardment.
Video footage obtained by Reuters showed wreckage at the Al-Shifa hospital, which staff said had been hit by air and artillery strikes.
"The clinics department is out of service, the clinical care unit is out, the surgery unit is out, the incubator unit is out, the paediatric section is out, all of the departments of the hospital are completely out of service," a man identified as a medical worker said.
Much of Hamouria's population has fled and and almost half of the current residents are from elsewhere. Water and electricity have been unavailable since June 2016.
Saqba
Saqba, which has avoided the high levels of destruction suffered by neighbouring areas, has also come under sustained attack in February and March.
By December, 27% of its buildings had been either damaged or destroyed. That figure is likely to have increased.
More than half the population is made up of people who have fled other areas.
Water and electricity are unavailable.
Kafr Batna
Kafr Batna, where 21% of buildings had been damaged or destroyed by December, has been attacked again by government warplanes in the latest round of bombings.
A number of people have been killed.
Douma
Image copyrightAFP
Douma - the biggest town in the district - was not included in the UN's damage assessments in December. However, it has been hit badly in the latest round of air and artillery strikes.
Basema Abdullah, a widow huddled in a basement with her four children, told Reuters: "We are in desperate need for your prayers."
Douma is the largest town in Eastern Ghouta
Satellite imagery of Al-Biruni University Hospital, near Douma, appears to show a roadblock on a nearby highway.
McKenzie Intelligence Services analysts say it suggests the hospital is only accessible by areas still loyal to the government.
Roadblock at Al-Biruni University Hospital, near Douma
Satellite images also show a trench network has been constructed in Harasta, south-west of Douma, next to a military barracks.
Analysts say the trenches are likely occupied by rebel fighters, given their location, and would allow them to move around the area without being hit by shrapnel and out of the sight of observers who could call in artillery or air strikes.
Networks of trenches can be seen in residential areas
February 2018
December 2014
Humanitarian crisis
Aid workers have described how thousands of families are now living in underground basements and shelters - many without water, sanitation or ventilation systems, making children vulnerable to the spread of disease.
The government has allowed one humanitarian convoy into the Eastern Ghouta since late November, and there are severe shortages of food and extremely inflated prices.
A bundle of bread cost close to 22 times the national average, and 11.9% of children under five years old are acutely malnourished - the highest rate recorded in Syria since the beginning of the war.
Residents have described going days without eating, consuming non-edible plants, or reducing the size of their meals due to a lack of access to food.
The Syrian government has denied targeting civilians and insisted it is trying to liberate the Eastern Ghouta from "terrorists" - a term it has used to describe both jihadist militants and the mainstream rebel groups that dominate the enclave.